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The Increased Cardiac Risks of 'Trans' Hormones Differ According to the Sex Binary
As though it does exist and is important
In a development that should surprise absolutely no one who has paid attention, a new paper shows that people taking cross-sex hormones as part of a ‘trans identity’ face “significantly higher risk” of cardiac problems.
Comparing health data from 2,671 Danish ‘trans people’ in their early or mid-20s to a control group of 26,700, the authors found increased risk of heart disease in both the men and women who identify as ‘trans.’
“Transgender women taking estrogen had a 93% increased risk of heart problems versus control men, and a 73% higher risk when measured against control women,” the NY Post reports.
“Transgender men taking testosterone had a 2.2 times increased risk of cardiovascular ailments compared with control men, and a 63% increased risk compared with control women.”
So while the risk of cardiac problems almost doubles for men on estrogen, it more than triples for women on testosterone. Normal baseline cardiac risk is the same for both sexes. Men experience the increased risk earlier in life, whereas women are more likely to experience “atypical” symptoms during a cardiac event.
“High blood pressure and abnormal blood fats were the most common cardiovascular problems observed in the trans study subjects,” the Post observes. Normally, both risk factors for heart disease are a little bit more common in men than women.
These differences exist because the human heart differs by sex.
“Healthy women and men have distinctly different left ventricular (LV) dimensions and function, even after indexing for body size. Women have smaller LV chambers and accordingly lower stroke volumes,” reads a 2018 paper analyzing one type of cardiac event that is more common in women then men.
Humans develop from conception along one of two pathways (the human sex binary) according to “genes linked to the X and Y chromosomes, many of which encode regulatory factors, are expressed in cardiac progenitor cells and at every subsequent developmental stage.”
Human hearts are very complex and thousands of things can go wrong. Tissue in one area may be too thin, or too inelastic, or too thick or elastic. Furthermore, “the effect of the sex chromosome composition may explain why many congenital heart defects originating before gonad formation exhibit sex biases in presentation, mortality, and morbidity” even in the womb.
Just like the activists who think human sex is a hormone, heart doctors used to think that sex hormones account for all the differences in cardiac function between male and female patients. However, today research in this area is broadly focused on the effects of sex hormones on cardiomyocytes, the cells which contract the heart and make it beat.
Given this scientific background, it is hardly surprising that the cardiac consequences of cross-sex hormones are not shared equally. This gross human experiment in alchemical transubstantiation of flesh resembles what we might get if we put diesel into gasoline engines, and vice-versa, to see which set of engines coughs, sputters, and dies first.
The new paper, “Cardiovascular risk in Danish transgender persons: a matched historical cohort study,” is available online. Published last August, it is only now getting attention from a mainstream media outlet, whereas the TERFs have been talking about it for a while.
Although the authors see increased risks of cardiac problems in the transgender population, “the mechanism is undetermined,” and as noted there can be multiple mechanisms of injury from wrong-sex hormones.
Reacting to the Post story, Exulansic explains more about the development of the heart to adulthood, concluding that “there ain't no free lunch:”
In real terms, this risk ratio for trans-identifying men is the equivalent of 1.5% of men getting cardiovascular disease compared with 3% of trans identified men. This may not sound like much, but the average age of the trans identifying men in this study, which had an n=approximately 29,000 (of which about 10% were trans), was goddamn 22 for females and 26 for males. Because of course, they’re doing this to very young people. What’s the rate going to be when they’ve been on these drugs for 5 or 6 decades like Jazz Jennings was signed up for by Jeanette, via starting hormones in middle school? He’s going to get to find out.
Indeed, we are all going to find out. A generation of young people has been subject to a medical experiment, with medical consequences that will only emerge over time.
Exulansic has already published several examples of research pointing to cardiac issues in the future for ‘trans folks’ — along with other negative impacts, most of which accrue to women on testosterone.
In the years to come, we can all look forward to studies which confirm that reduced pancreatic activity in ‘trans men’ leads to diabetes and cancer.
Early hysterectomies will increase the risk of early onset dementia. Many elderly parents will have to care for daughters who forget they were ever ‘trans’ at least a few times every day. Mommy, where are my breasts? Daddy, why do I have a beard?
Stroke. Kidneys. Brain function. Advocates of wrong-sex hormones often accuse their critics of a prurient obsession with sex organs. However, the long-term health consequences of wrong-sex hormones affect every organ, not just the naughty/fun ones. Pick any organ in the human body, anywhere from hair to toe, and there is potential risk because the hormones are carcinogenic.
Clinicians have been screwing around with endocrine systems for long enough now that we have entered the ‘finding out’ stage of the disaster. Ironic, though tragic, that the whole alchemical experiment premised on a ‘sex spectrum’ has instead demonstrated the vital importance of the sex binary in human health.
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